Antimicrobial activities of actinomycetes isolated from unexplored regions of Sundarbans mangrove ecosystem

Researchers have identified a highly potent actinomycete strain, SMS_SU21, from the Sundarbans mangrove ecosystem, capable of producing antimicrobial compounds effective against a broad range of pathogens, including phytopathogens. This strain demonstrated remarkable antimicrobial activity with a minimum inhibitory concentration (MIC) value of 0.05 mg/ml and significant antioxidant activity (IC50: 0.242 ± 0.33 mg/ml). The bioactive compound responsible for these activities was purified using GC-MS analysis, highlighting the potential of this strain as a source of new broad-spectrum antimicrobial agents. The study involved isolating and screening 54 actinomycetes from unexplored regions of the Sundarbans, followed by polyphasic identification and metabolic profiling to determine their antimicrobial potential.

Sengupta, S., Pramanik, A., Ghosh, A., & Bhattacharyya, M. (2015). Antimicrobial activities of actinomycetes isolated from unexplored regions of Sundarbans mangrove ecosystem. BMC Microbiology, 15(1). https://doi.org/10.1186/s12866-015-0495-4