Research history and ancient DNA from Dr Granville’s Egyptian Mummy

Ancient DNA analysis of Dr Granville’s Egyptian mummy, dating to around 600 BC and originating from the necropolis of Thebes, reveals that tuberculosis was likely the principal cause of death. Using nested PCR targeting the IS6110 locus and mycolic acid detection in lung tissue and femurs, researchers identified Mycobacterium tuberculosis complex DNA, indicating a fatal pulmonary condition. While Dr Granville initially attributed her death to a benign ovarian cyst, modern histological examination suggests tuberculosis was the underlying factor. This study combines historical scientific records with advanced genetic techniques to shed light on ancient disease.

Donoghue, H. D. (2020). Research history and ancient DNA from Dr Granville’s Egyptian Mummy. Aegyptus et Pannonia VI. : Acta Symposii Anno 2019, 21–26. https://doi.org/10.71067/aepvi-2020-21-26